Patents

PME-1 as a Biomarker to Predict and Diagnose Endometrial Cancer and Gene Silencing of PME-1 to Inhibit Epithelial to Mesenchymal Transition. Rice, L., Pusey, M., Wandzioch, E., Marie Genevieve Bail, S., Lynn Werda, A., US Patent Number 9,657,349. Issued on 5/23/2017.

Novel Polypeptides that Bound to IL-23 Receptor and Inhibit Binding of IL-23 and Cell Signaling Thereof. Gallagher, G., Yu, R., Branzaitis, J., US Patent Number 9,605,027. Issued on 3/28/2017.

Metronidazole Resistance in Trichomonas Vaginalis and Single Nucleotide Polymorphism. Hilbert, D., Gygax, S., Adelson, M., Mordechai, E., Schuyler, J., Paulish-Miller, T., US Patent Number 9,593,384. Issued on 3/14/2017.

ELISA for Naturally-occurring Soluble Truncated Forms of IL-23 Receptor. Gallagher, G., Yu, R., Eskdale, J., Branzaitis, J., US Patent Number 00. Issued on 12/20/2016.

A Novel Repressor on IFN-l Promoter and siRNA Against CRX, GATA1 and EVI1 to Alter IFN-l Gene Activity. Gallagher, G., Siegel, R., Eskdale, J., US Patent Number 9,506,066. Issued on 11/29/2016.

Methods and Reagents that Specifically Detect, Distinguish and Quantify IFN-λ2 mRNA from IFN-λ3 mRNA in Humans. Gallagher, G., Gallagher, G. E., Eskdale, J., Siegel, R., US Patent Number 9,464,321. Issued on 10/11/2016.

Integrated Method for Collection and Maintenance of Detectability of a Plurality of Microbiological Agents in a Single Clinical Sample and for Handling a Plurality of Samples For Reportong a Sum of Diagnostic Results for Each Sample. Adelson, M., Mordechai, E., US Patent Number 9,464,310. Issued on 10/11/2016.

Antibiotic Resistance Profile for Neisseria gonorrhoeae and Use of Same in Diagnosis and Treatment of Gonorrhea. Balashov, S., Mordechai, E., Adelson, M., US Patent Number 9,297,048. Issued on 3/29/2016.

Methods and Compositions for Detecting and Identifying Species of Candida. Trama, J., Adelson, M., Mordechai, E., US Patent Number 9,267,170. Issued on 2/23/2016.

ELISA Detection of Urine DEK to Predict and Diagnose Bladder Cancer in Humans. Datta, A., Trama, J., US Patent Number 9,255,925. Issued on 2/9/2016.

A Method of Enhancing MIR-185 Expression to Reduce Low Density Lipoprotein/Cholesterol Accumulation in a Cell. Yang, M., Nickels, J., Liu, W, Ann Pellicane, C., US Patent Number 9,243,250. Issued on 1/26/2016.

Novel Haplotype Tagging Single Nucleotide Polymorphisms and Use of Same to Predict Childhood Lymphblastic Leukemia. Florence Davis, C., Tevfik Dorak, M., US Patent Number 9,212,395. Issued on 12/15/2015.

Anti-sense Oligonucleotides Targeted Against Exon 9 of IL-23 R alpha Gene and Method of Using Same to Induce Exon Skipping and to Treat Inflammatory Bowel Diseases. Gallagher, G., Yu, R., Brazaitis, J., US Patent Number 9,187,750. Issued on 11/17/2015.

Novel Polypeptides that Bound to IL-23 Receptor and Inhibit Binding of IL-23 and Cell Signaling Thereof. Gallagher, G., Yu, R., Brazaitis, J., US Patent Number 9,169,292. Issued on 10/27/2015.

A Novel Repressor on IFN-l Promoter and siRNA Against ZEB1 and BLIMP-1 to Increase IFN-l Gene Activity. Gallagher, G., Siegel, R., Eskdale, J., US Patent Number 9,163,238. Issued on 10/20/2015.

Oligonucleotides Useful in Methods for Detecting and Characterizing Aspergillus fumigatus. Trama, J., Adelson, M., Mordechai, E., US Patent Number 9,145,593. Issued on 9/29/2015.

SiRNA Targeting ETS1 and ELK1 and Method of Using Same in the Inhibition of CIP2A Gene in Cancer Treatment. Rice, L., Pallai, R., US Patent Number 9,139,829. Issued on 9/22/2015.

Anaplasma Translocated Protein-1 (ATS-1) and Sero-Detection of Anaplasma phagocytophilum. Dimitrov, D., Hoey, J., US Patent Number 9,134,324. Issued on 9/15/2015.

Detecting DNA Methylation of BCL2, CDKN2A and NID2 Genes to Predict Bladder Cancer in Humans. Scher, M.,Trama, J., US Patent Number 9,096,905. Issued on 8/4/2015.

Methods and Compositions for Detecting Serotypes of Chlamydia trachomatis Capable of Causing Lymphogranuloma Venereum. Trama, J., Mordechai, E., Adelson, M., US Patent Number 8,956,814. Issued on 2/17/2015.

Novel Polypeptides that Bound to IL-23 Receptor and Inhibit Binding of IL-23 and Cell Signaling Thereof. Gallagher, G., Yu, R., Brazais, J., US Patent Number 8,946,150. Issued on 2/3/2015.

Methods and Compositions Related Thereto for Detecting and Identifying Distinct Species of Nucleic Acids from Causative Agents. Adelson, M., Feola, M., Trama, J., Mordechai, E., US Patent Number 8,932,832. Issued on 1/13/2015.

A Novel Repressor on IFN-Lambda Promoter and siRNA Against ZEB1 and BLIMP-1 to Increase IFN-Lambda Gene Activity. Gallagher, G., Siegel, R., Eskdale, J., Swider, A., US Patent Number 8,933,049. Issued on 1/13/2015.

CIP2A as a Biomarker in Detection of Cervical Cancer. Huang, L., Trama, J., US Patent Number 8,900,813. Issued on 12/2/2014.

Hemolysin and its Protein Fragments in Sero-detection of Anaplasma phagocytophilum. Hoey, J., Dimitrov, D., Huang, L., Adelson, M., Mordechai, E., US Patent Number 8,859,722. Issued on 10/14/2014.

A Novel Repressor on IFN-Lambda Promoter and siRNA Against ZEB1 and BLIMP-1 to Increase IFN-Lambda Gene Activity. Eskdale, J., Gallagher, G., Siegel, R., US Patent Number 8,802,648. Issued on 8/12/2014.

A Method of Determining Susceptibility of a Tumor Cell to a Chemotherapeutic Agent: Novel Use of Herpes Simplex Virus. Blaho, J., US Patent Number 8,778,331. Issued on 7/15/2014.

Ex-vivo Treatment of Peripheral Blood Leukocytes with IFN-Lambda. Gallagher, G., Gallagher, J., Dai, J., Megjugorac, N., Gallagher, G., US Patent Number 8,771,666. Issued on 7/8/2014.

Detection of a Specific DEK Isoform as a Urine-Based Biomarker for Bladder Cancer. Antara Datta, A., Trama, J., US Patent Number 8,741,582. Issued on 6/3/2014.

METRONIDAZOLE RESISTANCE IN TRICHOMONAS VAGINALIS AND SINGLE NUCLEOTIDE POLYMORPHISMS. Hilbert, D., Gygax, S., Adelson, M., Mordechai, E., Schuyler, J., Paulish-Miller, T., US Patent Number 8,741,563. Issued on 6/3/2014.

Method of Determining Types I, II, III, IV or V of Methicillin-resistant Staphylococcus aureus (MRSA) in a Biological Sample. Gygax, S., Overmeyer, C., DeSalvia, L., Adelson, M., Eli Mordechai, E., US Patent Number 8,715,936. Issued on 5/6/2014.

DEK as a Urine Based Biomarker for Bladder Cancer. Datta, A., Trama, J., US Patent Number 8,658,376. Issued on 2/25/2014.

Anti-sense Oligonucleotides Targeted Against Exon 9 of IL-23 R alpha Gene and Method of Using Same to Induce Exon Skipping and to Treat Inflammatory Bowel Diseases. Gallagher, G., Yu, R., Brazaitis, J., US Patent Number 8,618,070. Issued on 12/13/2013.

Recombinant Fragments and Synthetic Peptides of 17-kDa Polypeptide Useful in Detecting Bartonella henselae. Huang, L., Hoey, J., Adelson, M.E., Mordechai, E., US Patent Number 8,283,439. Issued on 11/12/2013.

A Detection Kit Containing A Novel Recombinant 15-kDA Polypeptide Useful For Detecting Human Infection with Bartonella Henselae. Hoey, J., Venit, H., Adelson, M.E., Mordechai, E., Valois-Cruz, F., US Patent Number 8,580,271. Issued on 11/12/2013.

Methods and Compositions for Detecting and Identifying Species of Candida. Trama, J., Adelson, M.E., Mordechai, E., US Patent Number 8,501,408. Issued on 8/6/2013.

Anaplasma Translocated Protein-1 (ATS-1) and Sero-Detection of Anaplasma phagocytophilum. Hoey, J., Dimitrov, D., US Patent Number 8,455,211. Issued on 6/4/2013.

Splice Variants of Human IL-23 Receptor (IL-23R) mRNA and Use of a Delta 9 Isoform in Predicting Inflammatory Bowel Diseases. Gallagher, G.,Yu, R., Kan, S., Mancini, G., US Patent Number 8,404,824. Issued on 3/26/2013.

Methods and Compositions for Detecting Serotypes of Chlamydia trachomatis Capable of Causing Lymphogranuloma Venereum. Feola, M., Trama, J., Mordechai, E., Adelson, M.E., US Patent Number 8,394,936. Issued on 3/12/2013.

Single Nucleotide Polymorphisms as Genetic Markers for Childhood Leukemia. Dorak, M.T., Ucisik-Akkaya, E., Davis, C., Ngoc Do., T., US Patent Number 8,394,587. Issued on 3/12/2013.

Compositions and Methods for Detecting Cryptococcus neoformans. Feola, M., Adelson, M.E., Mordechai, E., Entwistle, J., US Patent Number 8,377,656. Issued on 2/19/2013.

Ex-vivo Treatment of Peripheral Blood Leukocytes with IFN-Lambda. Gallagher, G., Eskdale, J., Srinivas, S., Dai, J., Megjugorac, N., Gallagher, G.E., US Patent Number 8,354,125. Issued on 1/15/2013.

A Novel Repressor on IFN-l Promoter and siRNA Against ZEB1 and BLIMP-1 to Increase IFN-l Gene Activity. Gallagher, G., Siegel, R., Eskdale, J., US Patent Number 8,349,808. Issued on 1/8/2013.

Type IV Secretion System Proteins in Sero-Detection of Anaplasma phagocytophilum. Hoey, J., Dimitrov, D., Huang, L., Adelson, M.E., Mordechai, E., US Patent Number 8,338,190. Issued on 12/25/2012.

Type IV Secretion System Proteins in Sero-Detection of Anaplasma phagocytophilum. Hoey, J. Dimitrov, D., Huang, L., Adelson, M.E., Mordechai, E., US Patent Number 8,323,907. Issued on 12/4/2012.

Babesia microti Genomic Clones Containing Novel Antigens Useful in the Diagnosis of Babesiosis. Hoey, J., Venit, H., Adelson, M.E., Mordechai, E., Valois-Cruz, F., US Patent Number 8,178,310. Issued on 10/9/2012.

Novel Recombinant 15-kDa Polypeptide and Use of Same in Detecting Human Infection with Bartonella henselae. Hoey, J., Venit, H., Adelson, M.E., Mordechai, E., Valois-Cruz, F., US Patent Number 8,268,569. Issued on 9/18/2012.

Protein Fragments of virB10 and Sero-Detection of Anaplasma Phagocytophilum. Hoey, J. Dimitrov, D., Huang, L., Adelson, M.E., Mordechai, E., US Patent Number 8,283,130. Issued on 9/9/2012.

Ex-vivo Treatment of Peripheral Blood Leukocytes with IFN-Lambda. Gallagher, G., Megjugorac, N., Gallagher, G.E., US Patent Number 8,282,964. Issued on 9/9/2012.

Hemolysin and its Protein Fragments in Sero-detection of Anaplasma phagocytophilum. Hoey, J., Dimitrov, D., Huang, L., Adelson, M.E., Mordechai, E., US Patent Number 8,257,938. Issued on 9/4/2012.

Detection of Penicillin Tolerance in Group B Streptococcus: Single Nucleotide Polymorphisms in Penicillin Binding Protein 4. Gygax, S., Prasa, A., Adelson, M.E., Mordechai, E., US Patent Number 8,247,170. Issued on 8/21/2012.

Protein Fragments of virB10 and Sero-Detection of Anaplasma Phagocytophilum. Hoey, J., Dimitrov, D., Huang, L., Adelson, M.E., Mordechai, E., US Patent Number 8,389,678. Issued on 7/19/2012.

Splice Variants of Human IL-23 Receptor (IL-23R) mRNA and Use of a Delta 9 Isoform in Predicting Inflammatory Bowel Diseases. Gallagher, G.,Yu, R., Kan, S., Mancini, G., US Patent Number 8,206,925. Issued on 6/26/2012.

Compositions and Methods for Detecting Borrelia afzeli. Feola, M., Adelson, M.E., Mordechai, E., Novak, L., US Patent Number 8,206,930. Issued on 6/26/2012.

Babesia microti Genomic Clones Containing Novel Antigens Useful in the Diagnosis of Babesiosis. Hoey, J., Venit, H., Adelson, M.E., Mordechai, E., Valois-Cruz, F., US Patent Number 8,388,981. Issued on 5/15/2012.

Antibodies Specific to Antigens of Bartonella henselae and Use of These Antigens in Immunoassays. McCool, T., Chang Loa, C., Adelson, M.E., Mordechai, E., US Patent Number 8,101,367. Issued on 1/24/2012.

Methods and Compositions Related Thereto for Detecting and Indentifying Distinct Species of Nucleic Acids from Causative Agent. Adelson, M.E., Feola, M., Trama, J., Mordechai, E., US Patent Number 8,030,032. Issued on 10/4/2011.

Compositions and Methods for Detecting Cryptococcus neoformans. Feola, M., Adelson, M.E., Mordechai, E., US Patent Number 7,989,186. Issued on 10/2/2011.

Compositions and Methods for Detecting Borrelia afzeli. Feola, M., Adelson, M.E., Mordechai, E., Novak, L., US Patent Number 8,026,056. Issued on 9/27/2011.

Method for Determining Azole Resistance in Candida glabrata. Gygax, S., Vermitsky, J.P., Self, M., Adelson, M.E., Mordechai, E., US Patent Number 8,021,846. Issued on 9/20/2011.

Compositions and Methods for Detecting Atopobium vaginae. Trama, J., Adelson, M.E., Mordechai, E., US Patent Number 7,745,595. Issued on 6/29/2010.

Antibodies Specific to Antigens of Bartonella henselae and Use of These Antigens in Immunoassays. McCool, T., Chang Loa, C., Adelson, M.E., Mordechai, E., US Patent Number 7,727,711. Issued on 6/1/2010.